Protons for Craniospinal Radiation: Are Clinical Data Important?
International Journal of Radiation Oncology * Biology * Physics
Outcomes for pediatric cancer patients have steadily improved over the decades as a result of meticulously conducted clinical trials. The pediatric oncology community has sought to design such trials not only to increase cure rates but also to maximize health-related quality of life in the developing child and the adult survivor. A generation of cured patients now exists, and we have started to grasp the full scope of late effects and survivorship issues that these patients encounter. It is incumbent on our field to explore all techniques and technologies that may enhance our ability to improve the therapeutic ratio. Given the magnitude of the stakes, it is clear that, as we investigate new technologies and their impact on outcome, we must do so with the same rigorous methods of scientific testing and peer review that have been so successful in the clinical research that has led us to our present state-of-the-art care.
Original Article: http://www.redjournal.org/article/S0360-3016(13)00629-9/abstract?rss=yes
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