Wednesday, October 22, 2014

Primary Intraventricular Central Nervous System Rhabdomyosarcoma

Primary Intraventricular Central Nervous System Rhabdomyosarcoma
Pediatric Neurology

A 10 year old girl presented with one week of new-onset headache and vomiting. Neurologic examination revealed wide-based ataxic gait. Computed tomography (CT) demonstrated a primary intraventricular mass with obstructive hydrocephalus (Figure 1A). The mass showed reduced diffusivity and homogeneous enhancement on magnetic resonance imaging (MRI) (Figure 1B-E). The patient underwent gross total resection of the tumor. Pathology demonstrated a malignant tumor characterized by densely cellular sheets of large eccentrically-placed vesicular nuclei, brisk mitotic activity, and rare cytoplasmic cross-striations.

Original Article: http://www.pedneur.com/article/S0887-8994(14)00513-X/abstract?rss=yes

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