Neuro-Oncology: [Correspondence] Stereotactic radiosurgery for patients with brain metastases

Wednesday, May 28, 2014

[Correspondence] Stereotactic radiosurgery for patients with brain metastases – Authors' reply

The Lancet Oncology

We thank Filippo Alongi and colleagues for their interest in our work. We are aware that there has been a debate for more than 20 years as to whether it is meaningful to calculate survival after stereotactic radiosurgery in a cohort, because about 90% of patients died in our study due to extracerebral disease progression after stereotactic radiosurgery for brain metastases. However, overall survival is still the most certain endpoint, as reported by Korn and colleagues, and the majority of previous studies have used overall survival to assess results after stereotactic radiosurgery.

Original Article: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)70221-9/fulltext?rss=yes