[Articles] Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial
The Lancet Oncology
In patients with painful bone metastases requiring repeat radiation therapy, treatment with 8 Gy in a single fraction seems to be non-inferior and less toxic than 20 Gy in multiple fractions; however, as findings were not robust in a per-protocol analysis, trade-offs between efficacy and toxicity might exist.
Original Article: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(13)70556-4/abstract?rss=yes
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