A call for "negative" outcome studies
Neurology recent issues
Human nature, being what it is, leads to the pernicious phenomenon in the scientific literature of publication bias. We are much more excited and motivated to report our successes than our failures. This is a particularly troublesome tendency when it comes to clinical trials. Studies that fail to reject the null hypothesis are more likely to languish on in draft form and never get published.
Original Article: http://www.neurology.org/cgi/content/short/82/1/11?rss=1
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