[Articles] The sex hormone system in carriers of BRCA1/2 mutations: a case-control study
The Lancet Oncology
Carriers of BRCA1/BRCA2 mutations are exposed to higher titres of oestradiol and progesterone—known risk-factors for breast cancer. Higher titres of oestradiol in carriers are compatible with this hormone having a role in ovarian carcinogenesis in such women. Our findings could not be explained by differential contraceptive pill use.
Original Article: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(13)70448-0/abstract?rss=yes
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