In recent years, endoscopic approaches to the pituitary and skull base are being used with increasing frequency for pituitary tumours and other tumours originating in the anterior skull base.
Ammirati and colleagues report the results of their meta-analysis comparing the results of the short-term outcome of pituitary surgery performed using a purely endoscopic approach versus a microscopic approach. They included comparison of mortality, extent of tumour removal and complications (cerebrospinal fluid leak, meningitis, vascular complications, visual complications, diabetes insipidus, hypopituitarism and cranial nerve injury) in their analysis. They conclude that the only significant difference with these two approaches is that the incidence of vascular injury was increased with endoscopic surgery. The types of vascular injury included in the analysis were, in general, potentially serious complications ('Vascular complications included carotid or other vessels injury, intracerebral hematoma, or any symptomatic intratumoural or intrasellar hemorrhage. Venous bleeding from the cavernous...
Original Article: http://jnnp.bmj.com/cgi/content/short/84/8/827?rss=1
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